Neuropsychological functioning in early-onset first-episode psychosis

Journal article


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Publication Details

Subtitle: Comparison of diagnostic subgroups
Author list: Bombin I
Publisher: Springer (part of Springer Nature): Springer Open Choice Hybrid Journals
Publication year: 2010
Volume number: 260
Issue number: 3
Start page: 225
End page: 233
Number of pages: 9
ISSN: 0940-1334
Languages: English-Great Britain (EN-GB)


The aims of this study were to examine the nature and extent of
cognitive impairment in first-episode early-onset psychosis (FE-EOP)
soon after their stabilisation and to search for potential differences
according to specific diagnostic sub-groups of patients. As part of a
Spanish multicentre longitudinal study, 107 FE-EOP patients and 98
healthy controls were assessed on the following cognitive domains:
attention, working memory, executive functioning, and verbal learning
and memory. Three diagnostic categories were established in the patient
sample: schizophrenia (n = 36), bipolar disorder (n = 19), and other
psychosis (n = 52). Patients performed significantly worse than controls
in all cognitive domains. The three diagnostic sub-groups did not
differ in terms of impaired/preserved cognitive functions or degree of
impairment. FE-EOP patients show significant cognitive impairment that,
during this early phase, seems to be non-specific to differential


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Last updated on 2019-13-08 at 00:45