Insight correlates in child- and adolescent-onset first episodes of psychosis




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Details zur Publikation

Untertitel: Results from the CAFEPS study
Autorenliste: Bombin I
Verlag: Cambridge University Press (CUP): STM Journals
Jahr der Veröffentlichung: 2009
Bandnummer: 39
Heftnummer: 9
Erste Seite: 1433
Letzte Seite: 1445
Seitenumfang: 13
ISSN: 0033-2917
Sprachen: Englisch-Vereinigtes Königreich (EN-GB)


Background. The correlates of insight in early-onset psychosis have
received little previous attention. Method. We studied clinical
correlates of insight in a sample of 110 adolescent recent-onset
psychosis patients (mean age 15.53 years; psychotic symptoms present for
<6 months). Insight was measured with the Scale to Assess
Unawareness of Mental Disorder (SUMD) at baseline, 6 months and 12
months follow-up. Results. Insight improved over the early phases of the
illness, in parallel with psychopathological improvement. Poor insight
at baseline and 6 months correlated with poor functioning at 6 and 12
months respectively. Schizophrenia patients had poorer insight than
patients with bipolar disorder at 6 and 12 months but not at baseline.
Logistic and linear regressions were used to predict 12-month diagnoses
and functioning based on insight measurements. Baseline awareness of
illness was a significant predictor for diagnosis [odds ratio (OR) 1.4,
95% confidence interval (CI) 1.05-1.97]. Treatment compliance at 6
months did not correlate with baseline SUMD subscores, but correlated
with insight into having a disorder (Spearman's ρ=0.21, p=0.039), its
consequences (Spearman's ρ=0.28, p=0.006) and the need for treatment
(Spearman's ρ=0.26, p=0.012) at 6 months. The 'attribution of symptoms'
dimension of insight is poorly correlated with other insight dimensions
and with other clinical variables. Conclusions. Poor insight correlates
with symptom severity and global functioning but also has some trait
value for schizophrenia, which is apparent once acute psychotic
symptomatology is not prominent. A multi-dimensional approach to the
assessment of insight is necessary, as different dimensions are
influenced by different factors


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Zuletzt aktualisiert 2019-13-08 um 00:45