Nuevas aportaciones a la neurobiología del trastorno por déficit de atención con hiperactividad desde la magnetoencefalografía.

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Publication Details

Author list: Capilla-González, A., Pazo, P., Campo, P., Maestú, F., Fernández, A., Fernández-González, S., Ortiz, T.
Publisher: Cesar Viguera
Publication year: 2005
Journal: Revista de Neurologia (0210-0010)
Volume number: 40
Issue number: Suppl 1
Start page: S43
End page: 47
ISSN: 0210-0010
Languages: Spanish-Spain (ES-ES)


INTRODUCTION AND DEVELOPMENT: Current theories postulate that the core
cognitive deficit in attention-deficit/hyperactivity disorder (ADHD) is
an executive dysfunction. Neuroimaging studies on the whole have
provided both anatomical and functional evidence supporting the
fronto-striatal dysfunction hypothesis in ADHD. However, recent
neuroimaging studies have found anatomical and functional impairments in
posterior cortical regions, such as the inferior parietal and posterior
temporal cortices, which have been related to a deficit in selective
attention. Event related potential (ERP) studies show that ADHD children
have an impairment in early components (within the first 200 ms of
processing), such as P1 or N1, both of which are sensitive to selective
attention effects. These findings cast doubt regarding the
fronto-striatal/executive dysfunction as the core deficit in ADHD.
CONCLUSIONS: One of the main objectives of ADHD research is the search
for its core cognitive deficit and the neural networks underlying it,
because it has important repercussions over ADHD diagnosis and
treatment. High temporal resolution techniques, such as ERP or
magnetoencephalography may be particularly useful in distinguishing the
precise moment of cognitive processing during which the brain activity
of children with ADHD begins to be impaired. As a consequence, this may
help to elucidate the core cognitive deficit in ADHD.


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Last updated on 2019-13-08 at 00:16